I have a popup "Cannot Start Application"

When starting scanning, i got the following popup:

Clicking on details can result into many possibilities.

Possible solutions are: ERROR DETAILS

                Following errors were detected during this operation.

                * [8/11/2013 14:04:59] System.Deployment.Application.InvalidDeploymentException (Manifest)

                               - Your Web browser settings do not allow you to run signed applications.

                               - Source: System.Deployment

                               - Stack trace:

                                               at System.Deployment.Application.ApplicationActivator.BrowserSettings.Validate(String manifestPath)

                                               at System.Deployment.Application.ApplicationActivator.PerformDeploymentActivation(Uri activationUri, Boolean isShortcut, String textualSubId, String deploymentProviderUrlFromExtension, BrowserSettings browserSettings, String& errorPageUrl)

                                               at System.Deployment.Application.ApplicationActivator.ActivateDeploymentWorker(Object state)